PhD Students

Area of Research:  Regulation of Kinetochore-Microtubule interactions

My work focuses on the molecular regulators that maintains proper kinetochore-microtubule attachment. I mainly investigate the role of the +TIP proteins in the structural organization of outer kinetochore and its link to chromosome segregation defects.

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Area of Research:   Role of E3 ubiquitin ligases in regulation of spindle assembly checkpoint proteins

My research focuses on understanding the role of novel E3 ubiquitin ligases in the regulation of SAC proteins and during mammalian cell division.

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Area of Research:   Regulation of centrosome bio-genesis and its associated signaling pathways

My work aims at exploring the cellular consequences of deregulation in centrosomal proteins and the cell stage-specific recruitment of key centriole duplication factors.

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Area of Research:   Regulation of expansion of fibrous corona layer of kinetochores on un-attached kinetochores

My research study focuses on identification and characterization of kinetochore associated proteins in the regulation of fibrous corona expansion on un-attached kinetochores during early mitosis.

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Area of Research: Regulation of protein complexes in centrosomal duplication

My research focus is to understand how several proteins associate or interact to form complexes and help mediate the duplication of centrosomes. I am specifically inclined to the kinase activities and site-specific phosphorylation of these proteins, which leads to the initiation of the formation of the daughter centriole.

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Area of Research: Regulation of Kinetochore-Microtubule Interaction

My research study focuses on understanding the molecular mechanisms at the Kinetochore-microtubule interface assisting the fidelity of chromosome segregation during mitosis.

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Area of Research: Molecular understanding of ciliogenesis

Primary cilium is the tiny signalling hub of the cell and that’s what fascinates me. My works focus on the understanding of molecular regulations of ciliogenesis in mammalian cells especially the involvement of centrosomal proteins in the process. 

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Major Project Students