Publications

Peer reviewed articles

  1. Energy producing metabolic pathways in functional regulation of the hematopoietic stem cells. Roy IM, Biswas A, Verfaillie CM, Khurana S. IUBMB Life 2018. In Press
  1. Generation of hepatocyte and endocrine pancreatic-like cells from human induced endodermal progenitor cells. Sambathkumar R, Akkerman R, Dastidar S, Roelandt P, Kumar M, Bajaj M, Rosa AM, Helsen N, Vanslembrouck V, Kalo E, Khurana S, Laureys J, Gysemans C, Faas MM, de Vos P, Verfaillie CM. PLoS One. 2018 May 11;13(5):e0197046.
  1. Multipotent adult progenitor cells improve the hematopoietic function in myelodysplasia. Roobrouck VD, Wolfs E, Delforge M, Broekaert D, Chakraborty S, Sels K, Vanwelden T, Holvoet B, Lhoest L, Khurana S, Pandey S, Hoornaert C, Ponsaerts P, Struys T, Boeckx N, Vandenberghe P, Deroose CM, Verfaillie CM. Cytotherapy. 2017 Jun;19(6):744-755.
  1. Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function. Manesia JK, Franch M, Tabas-Madrid D, Nogales-Cadenas R, Vanwelden T, Van Den Bosch E, Xu Z, Pascual-Montano A, Khurana S, Verfaillie CM. Stem Cells Dev. 2017 Apr 15;26(8):573-584.
  1. Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis. Khurana S, Schouteden S, Manesia JK, Santamaria-Martínez A, Huelsken J, Lacy-Hulbert A, Verfaillie CM. Nat Commun. 2016 Dec 1;7:13500.
  1. The effects of proliferation and DNA damage on hematopoietic stem cell function determine aging. Khurana S. Dev Dyn. 2016 Jul;245(7):739-50. Review.
  1. Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways. Manesia JK, Xu Z, Broekaert D, Boon R, van Vliet A, Eelen G, Vanwelden T, Stegen S, Van Gastel N, Pascual-Montano A, Fendt SM, Carmeliet G, Carmeliet P, Khurana S, Verfaillie CM. Stem Cell Res. 2015 Nov;15(3):715-721.
  1. Contribution of different bone marrow-derived cell types in endometrial regeneration using an irradiated murine model. Gil-Sanchis C, Cervelló I, Khurana S, Faus A, Verfaillie C, Simón C. Fertil Steril. 2015 Jun;103(6):1596-605.e1.
  1. Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia. Raitano S, Ordovàs L, De Muynck L, Guo W, Espuny-Camacho I, Geraerts M, Khurana S, Vanuytsel K, Tóth BI, Voets T, Vandenberghe R, Cathomen T, Van Den Bosch L, Vanderhaeghen P, Van Damme P, Verfaillie CM. Stem Cell Reports. 2015 Jan 13;4(1):16-24.
  1. FANCA knockout in human embryonic stem cells causes a severe growth disadvantage. Vanuytsel K, Cai Q, Nair N, Khurana S, Shetty S, Vermeesch JR, Ordovas L, Verfaillie CM. Stem Cell Res. 2014 Sep;13(2):240-50.
  1. SMAD signaling regulates CXCL12 expression in the bone marrow niche, affecting homing and mobilization of hematopoietic progenitors. Khurana S, Melacarne A, Yadak R, Schouteden S, Notelaers T, Pistoni M, Maes C, Verfaillie CM. Stem Cells. 2014 Nov;32(11):3012-22.
  1. Wnt5a does not support hematopoiesis in stroma-free, serum-free cultures. Schaap-Oziemlak AM, Schouteden S, Khurana S, Verfaillie CM. PLoS One. 2013;8(1):e53669.
  1. Glypican-3-mediated inhibition of CD26 by TFPI: a novel mechanism in hematopoietic stem cell homing and maintenance. Khurana S, Margamuljana L, Joseph C, Schouteden S, Buckley SM, Verfaillie CM. Blood. 2013 Apr 4;121(14):2587-95.
  1. A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression. Khurana S, Buckley S, Schouteden S, Ekker S, Petryk A, Delforge M, Zwijsen A, Verfaillie CM. Blood. 2013 Jan 31;121(5):781-90.
  1. Hepatocyte nuclear factor-4alpha induces transdifferentiation of hematopoietic cells into hepatocytes. Khurana S, Jaiswal AK, Mukhopadhyay A. J Biol Chem. 2010 Feb 12;285(7):4725-31.
  1. Hematopoietic progenitors from early murine fetal liver possess hepatic differentiation potential. Khurana S, Mukhopadhyay A. Am J Pathol. 2008 Dec;173(6):1818-27.
  1. In vitro transdifferentiation of adult hematopoietic stem cells: an alternative source of engraftable hepatocytes. Khurana S, Mukhopadhyay A. J Hepatol. 2008 Dec;49(6):998-1007.
  1. Characterization of the potential subpopulation of bone marrow cells involved in the repair of injured liver tissue. Khurana S, Mukhopadhyay A. Stem Cells. 2007 Jun;25(6):1439-47.
  1. MDR1 gene expression enhances long-term engraftibility of cultured bone marrow cells. Rentala S, Sagar Balla MM, Khurana S, Mukhopadhyay A. Biochem Biophys Res Commun. 2005 Sep 30;335(3):957-64.

Patents

  • TFPI in Maintenance/expansion of hematopoietic stem cells. US Patent publication no. US 2011/0311492 A1

Book chapters

  • Nagananda, A.M. Ali, I.M. Roy, C.M. Verfaillie, S. Khurana. Physico-chemical properties of the stem cell niche. In A. Muykhopadhyay ed. Regenerative Medicine, Springer India Pvt. Ltd. In Press.
  • Khurana, S. Bhaskar and A. Mukhopadhyay. Laboratory practice for the production of polyclonal and monoclonal antibodies. In A. Varma, R Oelmuller, eds. Advanced techniques in soil microbiology, Springer-verlag Berlin Heidelberg, 2007:73-91.
  • Khurana, S. Bhaskar and A. Mukhopadhyay. Modern techniques for analyzing immunological responses. In A. Varma, R Oelmuller, eds. Advanced techniques in soil microbiology, Springer-verlag Berlin Heidelberg, 2007:92-109.